Considerations for skin carcinogenesis experiments using inducible transgenic mouse models.
| Author | |
|---|---|
| Abstract |
:
This study was designed to estimate the percentage of non-malignant skin tumours (papillomas) progressing to malignant squamous cell carcinomas (SCCs) in a carcinogenesis study using established transgenic mouse models. In our skin cancer model, we conditionally induced oncogenic point mutant alleles of p53 and k-ras in undifferentiated, basal cells of the epidermis. |
| Year of Publication |
:
2018
|
| Journal |
:
BMC research notes
|
| Volume |
:
11
|
| Issue |
:
1
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| Number of Pages |
:
67
|
| Date Published |
:
2018
|
| URL |
:
https://bmcresnotes.biomedcentral.com/articles/10.1186/s13104-018-3182-3
|
| DOI |
:
10.1186/s13104-018-3182-3
|
| Short Title |
:
BMC Res Notes
|
| Download citation |
