Nanotechnology creates incredibly useful structures from individual atoms or molecules, which provides a new alternative and a possibly superior approach for the identification of oral health related problems and also in designing of more biocompatible dental materials with better properties and anticaries potential. Nanodentistry is striving its best to apply new advances in dental practice. The present article discusses the use of nanotechnology in dentistry and also the latest innovations in oral health care, nanoincorporated products, and issues of patient safety and occupational health.